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A case of topical imiquimod induced fatigue

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Abstract Topical imiquimod is used for a variety of common dermatologic lesions, including melanoma in-situ. As an immunomodulator, it is relatively well tolerated with minimal side effects, including scaling, erythema,… Click to show full abstract

Abstract Topical imiquimod is used for a variety of common dermatologic lesions, including melanoma in-situ. As an immunomodulator, it is relatively well tolerated with minimal side effects, including scaling, erythema, and edema. Here we present a rare systemic adverse effect, where our patient experienced debilitating severe fatigue when applying imiquimod to a single lesion. Clinicians should be mindful of this side effect and counsel patients appropriately.

Keywords: imiquimod induced; induced fatigue; imiquimod; topical imiquimod; case topical

Journal Title: Journal of Dermatological Treatment
Year Published: 2022

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