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Preparation and evaluation of radiolabeled gliclazide parenteral nanoemulsion as a new tracer for pancreatic β-cells mass.

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Purpose: The present investigation aims to develop and evaluate a radiopharmaceutical for targeting and assessing β-cells mass based on gliclazide, an antidiabetic drug that specifically binds the sulfonylurea receptor unique… Click to show full abstract

Purpose: The present investigation aims to develop and evaluate a radiopharmaceutical for targeting and assessing β-cells mass based on gliclazide, an antidiabetic drug that specifically binds the sulfonylurea receptor unique to the β-cells of the pancreas.

Keywords: cells mass; gliclazide parenteral; radiolabeled gliclazide; preparation evaluation; evaluation radiolabeled; mass

Journal Title: International journal of radiation biology
Year Published: 2023

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