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C18-Diterpenoid alkaloids from Delphinium anthriscifolium var. majus

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Abstract Five new C18-diterpenoid alkaloids, anthriscifoltines C-G (1–5), along with four known diterpenoid alkaloids anthriscifolcines C-F (6–9), were isolated from the extract of Delphinium anthriscifolium var. majus. Their structures were… Click to show full abstract

Abstract Five new C18-diterpenoid alkaloids, anthriscifoltines C-G (1–5), along with four known diterpenoid alkaloids anthriscifolcines C-F (6–9), were isolated from the extract of Delphinium anthriscifolium var. majus. Their structures were elucidated by extensive spectroscopic analyses (including 1D-, 2D-NMR, and HR-ESI-MS). Compounds 1–5 were also evaluated for their cytotoxic activity against MCF-7, HepG2, and H460 human cancer cell lines.

Keywords: var majus; delphinium anthriscifolium; diterpenoid alkaloids; anthriscifolium var; c18 diterpenoid

Journal Title: Journal of Asian Natural Products Research
Year Published: 2018

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