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Abstract A series of tanshinone IIA derivatives were synthesized through sulfonation, slat-forming, chlorination, and amidation reactions. Meanwhile, anti-myocardial injury activity was evaluated in vitro. D8 and D9 exhibited a slightly… Click to show full abstract
Abstract A series of tanshinone IIA derivatives were synthesized through sulfonation, slat-forming, chlorination, and amidation reactions. Meanwhile, anti-myocardial injury activity was evaluated in vitro. D8 and D9 exhibited a slightly higher anti-myocardial injury (5.78, 7.46 μM) activity compared with esmolol (8.12 μM). In addition, they also displayed a concentration-dependent inhibition on the anti-myocardial injury.
Keywords:
iia derivatives;
anti myocardial;
myocardial injury;
tanshinone iia
Journal Title: Journal of Asian Natural Products Research
Year Published: 2018
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Journal Title: Journal of Asian Natural Products Research
Year Published: 2018
Link to full text (if available)
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recommendations!