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Phenolic glycosides from Lavandual angustifolia

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Abstract Four new phenolic glycosides (1–4), together with 12 known ones (5–16), were isolated from the essential oil extraction waste of Lavandula angustifolia. Their structures were unequivocally determined by extensive… Click to show full abstract

Abstract Four new phenolic glycosides (1–4), together with 12 known ones (5–16), were isolated from the essential oil extraction waste of Lavandula angustifolia. Their structures were unequivocally determined by extensive spectroscopic analysis (1D and 2D NMR, HR-ESI-MS, UV, and optical rotation), chemical method, and comparison with data reported in the literature. The antioxidant activities of all compounds and new compounds’ influence on melanin content in B16 melanoma cells were examined, which indicated that compounds 1, 8, 13 had a certain degree of DPPH free radical scavenging activities, while only compound 2 could increase the melanin content with a dose-dependent manner.

Keywords: lavandual angustifolia; glycosides lavandual; phenolic glycosides

Journal Title: Journal of Asian Natural Products Research
Year Published: 2018

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