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Three new Lycopodium alkaloids from Lycopodium japonicum

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Abstract Three new Lycopodium alkaloids (1–3), together with 15 known alkaloids, were isolated from club moss Lycopodium japonicum. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D… Click to show full abstract

Abstract Three new Lycopodium alkaloids (1–3), together with 15 known alkaloids, were isolated from club moss Lycopodium japonicum. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR spectra. Compound 1 has an unusual β-oriented methyl group substituted at C-15 and an α-hydroxy cyclopentenone moiety. All new alkaloids were evaluated for the inhibition of T-type calcium channel.

Keywords: lycopodium alkaloids; lycopodium; three new; lycopodium japonicum; new lycopodium; alkaloids lycopodium

Journal Title: Journal of Asian Natural Products Research
Year Published: 2019

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