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Abstract Three new monoterpenoid indole alkaloids, kopsiaofficines A–D (1–3), were isolated from the 95% EtOH extract of the aerial parts of Kopsia officinalis. Their structures were established on the basis… Click to show full abstract
Abstract Three new monoterpenoid indole alkaloids, kopsiaofficines A–D (1–3), were isolated from the 95% EtOH extract of the aerial parts of Kopsia officinalis. Their structures were established on the basis of spectroscopic data. The isolated alkaloids were tested in vitro for cytotoxic activity against seven lung cancer cell lines. Consequently, alkaloids 1 and 3 exhibited some cytotoxic activities against all the tested tumor cell lines with IC50 values less than 20 µM.
Keywords:
indole alkaloids;
kopsia officinalis;
parts kopsia;
monoterpenoid indole;
aerial parts
Journal Title: Journal of Asian Natural Products Research
Year Published: 2019
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Journal Title: Journal of Asian Natural Products Research
Year Published: 2019
Link to full text (if available)
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recommendations!