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One new sesquiterpene pyridine alkaloid from the stems and leaves of Euonymus fortunei

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Abstract A new sesquiterpene pyridine alkaloid (1), along with four known compounds (2-5), were isolated from the stems and leaves of Euonymus fortunei. The new structure was determined by extensive… Click to show full abstract

Abstract A new sesquiterpene pyridine alkaloid (1), along with four known compounds (2-5), were isolated from the stems and leaves of Euonymus fortunei. The new structure was determined by extensive spectroscopic analyses (IR, UV, NMR, HRESIMS and ECD). In addition, compound 3 showed a stronger anti-respiratory syncytial virus (RSV) activity with an IC50 value of 1.20 ± 0.10 µM than the positive control ribavirin with an IC50 value of 5.62 ± 0.49 µM.

Keywords: euonymus fortunei; leaves euonymus; pyridine alkaloid; sesquiterpene pyridine; stems leaves; new sesquiterpene

Journal Title: Journal of Asian Natural Products Research
Year Published: 2020

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