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Isolation of a new steroid from phytochemical investigation on Caralluma lasiantha

Abstract A new steroid (acylated C21 pregnane steroid) was isolated from chloroform extract in phytochemical screening of Caralluma lasiantha. The isolated compound is found to be 3β-hydroxy-14β–(6′- carboxyphenyl)propionyloxypregn–5-en-20-one based on… Click to show full abstract

Abstract A new steroid (acylated C21 pregnane steroid) was isolated from chloroform extract in phytochemical screening of Caralluma lasiantha. The isolated compound is found to be 3β-hydroxy-14β–(6′- carboxyphenyl)propionyloxypregn–5-en-20-one based on spectroscopic studies (IR, 1H NMR, 13C NMR, DEPT, COSY, HSQC, HMBC and ESI-MS). The isolated new steroid was tested against four bacterial strains and the activity was related to the structure of the molecule. Graphical Abstract

Keywords: new steroid; caralluma lasiantha; isolation new; steroid phytochemical

Journal Title: Journal of Asian Natural Products Research
Year Published: 2022

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