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Armatenols A–C, new antioxidant isoflavanols from Colutea armata

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Abstract Armatenols A–C (1–3), new isoflavan-4-ols, have been isolated from the CHCl3-soluble sub-fraction of Colutea armata Hemsl. & Lace, along with two known compounds namely 8-methoxyvestitol (4) and colutequinone (5),… Click to show full abstract

Abstract Armatenols A–C (1–3), new isoflavan-4-ols, have been isolated from the CHCl3-soluble sub-fraction of Colutea armata Hemsl. & Lace, along with two known compounds namely 8-methoxyvestitol (4) and colutequinone (5), reported for the first time from this species. Their structures have been elucidated through spectroscopic techniques including MS, IR, UV, CD, 1 D and 2 D NMR. Compounds 1–2 invariably showed significant antioxidant activity using the methods of 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity (DPPH), Fe3+ reducing antioxidant power (FRAP) assay and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) radical scavenging activity (ABTS). Graphical Abstract

Keywords: isoflavanols colutea; armatenols new; antioxidant isoflavanols; colutea armata; new antioxidant; activity

Journal Title: Journal of Asian Natural Products Research
Year Published: 2022

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