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Two unusual novel iridoid glycosides, cornsecoside A (1) and cornsecoside B (2), were isolated from a 40% ethanol elution fraction of a 50% ethanol extract of Cornus officinalis fruit. Their… Click to show full abstract
Two unusual novel iridoid glycosides, cornsecoside A (1) and cornsecoside B (2), were isolated from a 40% ethanol elution fraction of a 50% ethanol extract of Cornus officinalis fruit. Their structures were determined by spectroscopic data analysis combined with hydrolysis and ECD spectroscopy. In addition, compounds 1 and 2 exhibited cytotoxic activity against Bel-7402 cells with IC50 values of 8.12 and 9.31 µM, and were neuroprotective against H2O2-induced SH-SY5Y cell injure at a concentration of 10 µM.
Keywords:
two unusual;
novel iridoid;
iridoid glycosides;
officinalis fruit;
unusual novel;
cornus officinalis
Journal Title: Journal of Asian natural products research
Year Published: 2022
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Journal Title: Journal of Asian natural products research
Year Published: 2022
Link to full text (if available)
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recommendations!