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Abstract DABCO (1,4-diaza-bicyclo[2,2,2]octane) was applied as an efficient catalyst for the one-pot three-component synthesis of highly functionalized cyclohexenones: 2-oxo-N,4,6-triarylcyclohex-3-enecarboxamides via the condensation between acetophenone/4-methylacetophenone, aromatic aldehydes, and acetoacetanilide in ethanol… Click to show full abstract
Abstract DABCO (1,4-diaza-bicyclo[2,2,2]octane) was applied as an efficient catalyst for the one-pot three-component synthesis of highly functionalized cyclohexenones: 2-oxo-N,4,6-triarylcyclohex-3-enecarboxamides via the condensation between acetophenone/4-methylacetophenone, aromatic aldehydes, and acetoacetanilide in ethanol at ambient condition. This methodology has a number of advantages such as high yields, short reaction times, clean work-up (just simple filtration), and mild reaction conditions.
Journal Title: Polycyclic Aromatic Compounds
Year Published: 2019
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