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Mechanochemical Approach for the Selective Synthesis of 1,2-Disubstituted Benzimidazoles and Their Molecular Docking Studies

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A greener, scalable and mild mechanochemical protocol has been developed using readily available aromatic aldehydes and o-phenylenediamine in the presence of urea nitrate catalyst to afford 1,2-dis... Click to show full abstract

A greener, scalable and mild mechanochemical protocol has been developed using readily available aromatic aldehydes and o-phenylenediamine in the presence of urea nitrate catalyst to afford 1,2-dis...

Keywords: selective synthesis; benzimidazoles molecular; mechanochemical approach; disubstituted benzimidazoles; synthesis disubstituted; approach selective

Journal Title: Polycyclic Aromatic Compounds
Year Published: 2020

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