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Discovery of Rhodanine and Thiazolidinediones as Novel Scaffolds for EGFR Inhibition: Design, Synthesis, Analysis and CoMSIA Studies

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This study reports, 35 novel rhodanine, its bioisosteres thiazolidinediones and is tested for EGFR inhibition. These molecules are designed by using a pharmacophore-based superimpose approach takin... Click to show full abstract

This study reports, 35 novel rhodanine, its bioisosteres thiazolidinediones and is tested for EGFR inhibition. These molecules are designed by using a pharmacophore-based superimpose approach takin...

Keywords: egfr inhibition; inhibition; thiazolidinediones novel; novel scaffolds; rhodanine thiazolidinediones; discovery rhodanine

Journal Title: Polycyclic Aromatic Compounds
Year Published: 2020

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