LAUSR

Abstract Bioceramic compositions of xMnO·(43 − x)CaO·42SiO2·9P2O5-6ZnO (where x = 2,4,6 and 8 mol%)were prepared by the sol gel process. Structure and surface morphology have been determined by X-Ray Diffraction, Fourier Transform Infrared and Field Emission Scanning Electron Microscopytechniques which have shown the significant hydroxyapatite growth after soaking in simulated body fluid (SBF) for 7 days. Degradation rate in SBF has also been investigated. The cellular behavior has been evaluated by using human osteosarcoma MG63 cell line. The surface charge of prepared samples has been determined by Zeta potential studies and found to be negative when immersed in simulated body fluid. The results indicate that our samples provide the friendly environment for cellular growth with maximum viability of 92%. The synthesized bioceramic compositions show potential for bone regeneration applications as implant materials.