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Reply: Cost-effectiveness of combination daclatasvir-sofosbuvir for treatment of genotype 3 chronic hepatitis C infection in the United States

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We acknowledge that older data were used in our model, which can be explained by the fact that we finalized the model inputs before the 2014 CDC statistics were published.… Click to show full abstract

We acknowledge that older data were used in our model, which can be explained by the fact that we finalized the model inputs before the 2014 CDC statistics were published. The updated age and sex distribution data are not materially different from the values we used in our analyses and, hence, the results based on the updated population characteristics are similar (i.e. daclatasvir-sofosbuvir dominates sofosbuvirribavirin). The baseline distribution of fibrosis and cirrhosis stages that we used, and that are presented in Table 1 of our paper, came from the McGarry et al. article (for all ages). We, however, rounded those values to whole numbers before using them in our model. We acknowledge the confusion caused by the inappropriate accuracy implied by the “.00” digits reported in Table 1 of our article.

Keywords: daclatasvir; daclatasvir sofosbuvir; reply cost; cost effectiveness; effectiveness combination

Journal Title: Journal of Medical Economics
Year Published: 2017

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