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Blockade of the CD47-SIRPα axis: a promising approach for cancer immunotherapy

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Macrophages are often the most abundant immune cell found in the tumor microenvironment, but are frequently associated with poor patient prognosis and considered detrimental to mounting an effectiv... Click to show full abstract

Macrophages are often the most abundant immune cell found in the tumor microenvironment, but are frequently associated with poor patient prognosis and considered detrimental to mounting an effectiv...

Keywords: sirp axis; blockade cd47; axis promising; promising approach; cd47 sirp; approach cancer

Journal Title: Expert Opinion on Biological Therapy
Year Published: 2019

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