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Abstract One new (named peniproline A, 1) and 11 known compounds were isolated from a culture of the endophytic fungus Penicillium decumbens CP-4. The structure of 1, featuring a phenylamine… Click to show full abstract
Abstract One new (named peniproline A, 1) and 11 known compounds were isolated from a culture of the endophytic fungus Penicillium decumbens CP-4. The structure of 1, featuring a phenylamine unit coupled with 2-pyrrolidone by forming a distinctive nitrogen-nitrogen bond, was elucidated based on extensive spectroscopic methods. Compound 1 was found to have cytotoxic effects against Bel-7402 and Hela cell lines with IC50 values of 8.1 and 15.5 μM, respectively.
Keywords:
endophytic fungus;
penicillium decumbens;
pyrrolidone;
fungus penicillium
Journal Title: Natural Product Research
Year Published: 2017
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Journal Title: Natural Product Research
Year Published: 2017
Link to full text (if available)
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recommendations!