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Abstract Two new isoprenylated xanthones, calodioscurin A (1) and B (2) were isolated from the stem bark of Calophyllum dioscurii P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide (3)… Click to show full abstract
Abstract Two new isoprenylated xanthones, calodioscurin A (1) and B (2) were isolated from the stem bark of Calophyllum dioscurii P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide (3) and methyl inophyllum P (4). The structures of two new compounds were determined based on their HRESIMS, IR, UV, 1D and 2D NMR spectral data. Compounds 1–4 were assayed on P-388 cells, compound 2 showed IC50 value 11.5 μM and categorised moderate activity.
Keywords:
two new;
isoprenylated xanthones;
new isoprenylated;
stem bark;
bark calophyllum;
calophyllum dioscurii
Journal Title: Natural Product Research
Year Published: 2019
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Journal Title: Natural Product Research
Year Published: 2019
Link to full text (if available)
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recommendations!