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Saponin with antibacterial activity from the roots of Albizia adianthifolia

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Abstract An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open… Click to show full abstract

Abstract An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128 μg/mL. Graphical Abstract

Keywords: roots albizia; antibacterial activity; albizia adianthifolia; saponin antibacterial; activity roots

Journal Title: Natural Product Research
Year Published: 2019

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