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A new p-terphenyl derivative from the fruiting bodies of Sarcodon imbricatus (L.) P. Karst

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Abstract A new p-terphenyl, 2',3'-diacetoxy-4,5,5',6',4'',5''-hexahydroxy-p-terphenyl (1), along with 12 known compounds were isolated from the fruiting bodies of Sarcodon imbricatus (Bankeraceae). Their structures were confirmed on the basis of extensive… Click to show full abstract

Abstract A new p-terphenyl, 2',3'-diacetoxy-4,5,5',6',4'',5''-hexahydroxy-p-terphenyl (1), along with 12 known compounds were isolated from the fruiting bodies of Sarcodon imbricatus (Bankeraceae). Their structures were confirmed on the basis of extensive spectroscopic analysis and comparison with the spectral data in the literature. Compound 1 exhibited weak cytotoxicity against colon cancer SW480 and leukemia HL-60 cell lines, with IC50 values of 55.02 ± 1.79 μM and 44.71 ± 2.15 μM, respectively. Graphical Abstract

Keywords: bodies sarcodon; fruiting bodies; sarcodon imbricatus; new terphenyl; terphenyl derivative; terphenyl

Journal Title: Natural Product Research
Year Published: 2019

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