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Polysaccharide from Caulerpa lentillifera: extraction optimization with response surface methodology, structure and antioxidant activities

Abstract Ultrasonic-assisted extraction based on Response Surface Methodology was applied to isolate a polysaccharide (CLP) from Caulerpa lentillifera obtained in the South China Sea and the highest yield of the… Click to show full abstract

Abstract Ultrasonic-assisted extraction based on Response Surface Methodology was applied to isolate a polysaccharide (CLP) from Caulerpa lentillifera obtained in the South China Sea and the highest yield of the crude polysaccharide was 11.8%. CLP consisted of xylose, galactose, glucose and glucuronic acid in a molar ratio of 2.00: 1.00: 0.26: 0.04, with a molecular weight of 115 kDa. The content of uronic acids and sulfate groups in CLP was 14.10% and 27.40%, respectively. CLP presented good radical scavenging activities against O2 ·-, DPPH radical, while the scavenging activities against OH· and ABTS radical were not so satisfying. Graphical Abstract

Keywords: methodology; extraction; caulerpa lentillifera; response surface; surface methodology

Journal Title: Natural Product Research
Year Published: 2019

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