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Two new 7, 20-epoxy-ent-kauranes from the aerial parts of Isodon eriocalyx.

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Two previously undescribed 7, 20-epoxy-ent-kauranes along with six known ent-kauranoids, were isolated from the aerial parts of Isodon eriocalyx. The structures of new compounds were established on the basis of… Click to show full abstract

Two previously undescribed 7, 20-epoxy-ent-kauranes along with six known ent-kauranoids, were isolated from the aerial parts of Isodon eriocalyx. The structures of new compounds were established on the basis of extensive spectroscopic analyses. Compound 2 could inhibit the production of interleukin - 1β (IL - 1β) in monosodium urate (MSU) and lipopolysaccharide (LPS) induced macrophages.

Keywords: epoxy ent; ent kauranes; isodon eriocalyx; parts isodon; aerial parts

Journal Title: Natural product research
Year Published: 2020

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