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New flavonoids and xanthone from the stem bark of Artocarpus rigidus blume and cytotoxicity.

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Three new flavonoids named artorigidinones A-C and a new xanthone named artorixanthone together with seven known compounds were isolated from the stem bark of Artocarpus rigidus Blume. Their structures were… Click to show full abstract

Three new flavonoids named artorigidinones A-C and a new xanthone named artorixanthone together with seven known compounds were isolated from the stem bark of Artocarpus rigidus Blume. Their structures were characterized by spectroscopic data. γ-Geranylapigenin exhibited cytotoxicity to a fibroblast-like cell line (SW1353) (IC50 < 0.32 µg/mL) stronger than a standard drug.

Keywords: artocarpus rigidus; bark artocarpus; stem bark; new flavonoids; rigidus blume

Journal Title: Natural product research
Year Published: 2020

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