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Five new secoiridoid glycosides, cornusphenosides E-I (1-5), were isolated and characterized from an active fraction of ethanol extract of the fruits of Cornus officinalis. Their structures were determined by extensive… Click to show full abstract
Five new secoiridoid glycosides, cornusphenosides E-I (1-5), were isolated and characterized from an active fraction of ethanol extract of the fruits of Cornus officinalis. Their structures were determined by extensive spectroscopic data analysis, including 2 D NMR and HRESIMS experiments. In the preliminary assay, compound 5 (when evaluated at 10 μM) showed the neuroprotective effect against H2O2-induced SH-SY5Y cell damage.
Keywords:
fruits cornus;
glycosides fruits;
secoiridoid glycosides;
cornus officinalis
Journal Title: Natural product research
Year Published: 2020
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Journal Title: Natural product research
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!