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A chemical investigation of Aspergillus californicus IBT 16748 led to the isolation of two new oxepine-pyrimidinone-ketopiperazine type nonribosomal peptides oxepinamides L (1) and M (2). Their structures were characterised by… Click to show full abstract
A chemical investigation of Aspergillus californicus IBT 16748 led to the isolation of two new oxepine-pyrimidinone-ketopiperazine type nonribosomal peptides oxepinamides L (1) and M (2). Their structures were characterised by spectroscopic analysis including HRESIMS, 1D and 2D NMR. The absolute structure of 1 was assigned by ECD calculation. The antibacterial and cytotoxic properties of 1 were evaluated.
Keywords:
ketopiperazine type;
two new;
aspergillus californicus;
oxepine pyrimidinone;
pyrimidinone ketopiperazine;
new oxepine
Journal Title: Natural product research
Year Published: 2020
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Journal Title: Natural product research
Year Published: 2020
Link to full text (if available)
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recommendations!