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Three new biflavonoids, umcephabiovins C - E (1 - 3), along with fourteen known compounds were isolated from the twigs and leaves of Cephalotaxus oliveri. Their structures and configurations were elucidated by UV, IR,… Click to show full abstract
Three new biflavonoids, umcephabiovins C - E (1 - 3), along with fourteen known compounds were isolated from the twigs and leaves of Cephalotaxus oliveri. Their structures and configurations were elucidated by UV, IR, NMR, ECD, and HR-ESI-MS spectra. Compounds 1 - 3 exhibited significant α-glucosidase inhibitory activity with IC50 values of 7.05 ± 2.66, 24.45 ± 4.73, and 1.84 ± 1.14 μM, respectively. Compound 11 showed moderate cytotoxicity against the BaF3/T315I cell line.
Keywords:
twigs leaves;
leaves cephalotaxus;
inhibitory activity;
glucosidase inhibitory;
cephalotaxus oliveri
Journal Title: Natural product research
Year Published: 2021
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Journal Title: Natural product research
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!