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Identification of the chemical constituents in Cullen corylifolium ethanolic extract by LC-MS/MS and GC-MS.

Cullen corylifolium has been used to treat bronchial asthma, vitiligo, nephritis and leucopenia from ancient times in China. However, its chemical composition has not been fully understood. In this study,… Click to show full abstract

Cullen corylifolium has been used to treat bronchial asthma, vitiligo, nephritis and leucopenia from ancient times in China. However, its chemical composition has not been fully understood. In this study, both LC-MS and GC-MS were used to identify the chemical composition in C. corylifolium. Consequently, 31 compounds were qualified by LC-MS/MS, 8 representative compounds of which were quantified, 62 compounds including hydrocarbons, terpenoids and coumarins were identified by GC-MS. Among a total of 93 compounds, 32 compounds (8 by LC-MS/MS and 24 by GC-MS) are undocumented for this herb. Our results will provide a crucial foundation for further studies related to its pharmaceutical activities and quality control.

Keywords: constituents cullen; cullen corylifolium; identification chemical; corylifolium ethanolic; corylifolium; chemical constituents

Journal Title: Natural product research
Year Published: 2021

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