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The total synthesis of the 16-membered Polyhydroxylated macrolide, Aspergillide D has been accomplished utilizing the Grignard reaction, Sharpless asymmetric epoxidation Regioselective ring opening of epoxy alcohol, Wittig olefination and Yamaguchi… Click to show full abstract
The total synthesis of the 16-membered Polyhydroxylated macrolide, Aspergillide D has been accomplished utilizing the Grignard reaction, Sharpless asymmetric epoxidation Regioselective ring opening of epoxy alcohol, Wittig olefination and Yamaguchi macrolactonisation as key steps. 3-butene-1-ol has been utilized as the starting material.
Keywords:
total synthesis;
synthesis aspergillide;
stereoselective total;
synthesis
Journal Title: Natural product research
Year Published: 2022
Link to full text (if available)
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Journal Title: Natural product research
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!