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A new sesquiterpenoid from the aconitum-derived fungus Aspergillus fumigatus M1.

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A new bergamotane sesquiterpenoid, fumigatanol (1), along with nine known compounds (2-10) were isolated from the Aconitum-derived fungus Aspergillus fumigatus M1. Their structures were established on the basis of extensive… Click to show full abstract

A new bergamotane sesquiterpenoid, fumigatanol (1), along with nine known compounds (2-10) were isolated from the Aconitum-derived fungus Aspergillus fumigatus M1. Their structures were established on the basis of extensive spectroscopic analyses, ECD experiment and NMR computational method. Antibacterial and cytotoxic activities of compound 1 were evaluated and no obvious antibacterial and cytotoxic activities were observed at concentrations of 256 μg/mL and 40.00 μM, respectively.

Keywords: aconitum derived; fungus aspergillus; aspergillus fumigatus; derived fungus; new sesquiterpenoid

Journal Title: Natural product research
Year Published: 2022

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