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A new colchinoid compound, identified as N-deacetyl-N-formylcornigerine (1), named glorigerine was isolated from the roots of Gloriosa superba, along with two known compounds. The structures of isolated compounds were elucidated… Click to show full abstract
A new colchinoid compound, identified as N-deacetyl-N-formylcornigerine (1), named glorigerine was isolated from the roots of Gloriosa superba, along with two known compounds. The structures of isolated compounds were elucidated by 1 D and 2 D NMR and HRMS experiments. Glorigerine (1) differed from cornigerine (6) by the presence of an N-formyl group instead of the N-acetyl group. Glorigerine (1) was found to have moderate cytotoxicity when tested against four human cancer cell lines.
Keywords:
isolation new;
colchinoid;
new cytotoxic;
cytotoxic colchinoid;
gloriosa superba;
colchinoid gloriosa
Journal Title: Natural product research
Year Published: 2022
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Journal Title: Natural product research
Year Published: 2022
Link to full text (if available)
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recommendations!