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Four new sesquiterpenoids, dstramonins A-D (1-4), and one new natural product (5), together with three known compounds (6-8), were isolated from the leaves of Datura stramonium L. The structures of… Click to show full abstract
Four new sesquiterpenoids, dstramonins A-D (1-4), and one new natural product (5), together with three known compounds (6-8), were isolated from the leaves of Datura stramonium L. The structures of new compounds were elucidated by extensive spectroscopic analysis and comparison with the literature. The cytotoxicity of isolates against LN229 cells was assessed and compounds 2-4, and 7 displayed cytotoxic activity with IC50 values ranging from 8.03 to 13.83 μM.
Keywords:
datura stramonium;
sesquiterpenoids leaves;
cytotoxicity sesquiterpenoids;
leaves datura
Journal Title: Natural product research
Year Published: 2023
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Journal Title: Natural product research
Year Published: 2023
Link to full text (if available)
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recommendations!