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An Argument for Protocolized Diagnosis and Management of COPD by GOLD Guidelines: Needs Modification and More Emphasis to be Given to ICS (Inhaled Corticosteroids) in Indian Subsets of COPD Patients

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Prospective interventional and observational study conducted after IRB approval in Pulmonary Medicine, MIMSR Medical College & Venkatesh chest hospital Latur during January 2014 to June 2017, included 600 symptomatic COPD… Click to show full abstract

Prospective interventional and observational study conducted after IRB approval in Pulmonary Medicine, MIMSR Medical College & Venkatesh chest hospital Latur during January 2014 to June 2017, included 600 symptomatic COPD cases diagnosed by GOLD guidelines (FEV1/FVC < 0.7) and FEV1 < 80% in all cases, eosinophilic predominance in sputum (4% or more), and having at least one exacerbation in last three years. All study cases received influenza vaccination before enrollment in study and received same treatment to all cases as ICS (inhaled corticosteroids) and LAMA (long acting antimuscarinic drug) combination (glycopyrronium bromide and salmeterol plus fluticasone in different dry powder inhalers). Statistical analysis was done by using Chi test and student’s t test.

Keywords: gold guidelines; ics inhaled; argument protocolized; copd; protocolized diagnosis; inhaled corticosteroids

Journal Title: COPD: Journal of Chronic Obstructive Pulmonary Disease
Year Published: 2019

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