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Optical anisotropy measurement of polymeric nanoparticle with polarization interferometric confocal microscope

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ABSTRACT This study proposes a polarization Interferometric nonlinear confocal microscope to analyze a single nanoparticle for drug delivery system (DDS). The system includes the Michelson-type interferometer in a nonlinear confocal… Click to show full abstract

ABSTRACT This study proposes a polarization Interferometric nonlinear confocal microscope to analyze a single nanoparticle for drug delivery system (DDS). The system includes the Michelson-type interferometer in a nonlinear confocal laser microscope. The microscope has characteristics of high resolution and high contrast. We have measured optical anisotropies in a 200-nm diameter polymeric nanoparticle with the microscope.

Keywords: polymeric nanoparticle; polarization interferometric; confocal microscope; microscope

Journal Title: Molecular Crystals and Liquid Crystals
Year Published: 2017

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