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Inflammatory Myofibroblastic Tumor of the Sigmoid Colon in an Infant: A Case Report and Literature Review

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Abstract Background: Inflammatory myofibroblastic tumor (IMT) infrequently involves the sigmoid colon, and has not previously been described in an infant sigmoid colon. Case report: An inflammatory myofibroblastic tumor arose from… Click to show full abstract

Abstract Background: Inflammatory myofibroblastic tumor (IMT) infrequently involves the sigmoid colon, and has not previously been described in an infant sigmoid colon. Case report: An inflammatory myofibroblastic tumor arose from the sigmoid colon of an 11-month-old boy, confirmed by anaplastic lymphoma kinase (ALK), smooth muscle actin (SMA) and desmin immunohistochemical staining. The patient recovered well after complete resection of the tumor. Discussion: Sigmoid IMT can occur in infancy. This eighth case is the youngest so far. The child did well after surgical resection.

Keywords: inflammatory myofibroblastic; myofibroblastic tumor; tumor; sigmoid colon

Journal Title: Fetal and Pediatric Pathology
Year Published: 2022

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