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A Two-in-One Tumor in the Adrenal: A Functional Adrenocortical Adenoma with Myelolipomatous Differentiation

Abstract Background Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together. Case report A 14-year-old girl presented with… Click to show full abstract

Abstract Background Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together. Case report A 14-year-old girl presented with the features of ACTH-independent endogenous Cushing syndrome. Abdominal CECT revealed a left adrenal 2.3 × 1.8 × 1.5 cm arterially enhancing nodular lesion with central hypodensity. Histologically, this was an ADA with oncocytic change and myelolipomatous differentiation/metaplasia. Discussion/Conclusion ADA with myelolipomatous differentiation/metaplasia can occur in the pediatric age group.

Keywords: myelolipomatous differentiation; two one; adrenocortical adenoma; differentiation; one tumor

Journal Title: Fetal and Pediatric Pathology
Year Published: 2022

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