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Malignant Pigmented Epithelioid Angiomyolipoma of the Kidney in a Child with Tuberous Sclerosis Complex

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Abstract Introduction: Pigmented epithelioid angiomyolipoma is a variant of epithelioid angiomyolipoma (EAML) that has not previously been described in children with tuberous sclerosis. Case presentation: A 15-year-old boy with tuberous… Click to show full abstract

Abstract Introduction: Pigmented epithelioid angiomyolipoma is a variant of epithelioid angiomyolipoma (EAML) that has not previously been described in children with tuberous sclerosis. Case presentation: A 15-year-old boy with tuberous sclerosis had a rapidly enlarging renal mass associated with a left lung nodule. Microscopically it was a pigmented EAML, confirmed by immunohistochemistry. Discussion/Conclusion: The pigmented variant of EAML can arise and metastasize from the kidney of a teenager with tuberous sclerosis.

Keywords: pigmented epithelioid; epithelioid angiomyolipoma; sclerosis; kidney; tuberous sclerosis

Journal Title: Fetal and Pediatric Pathology
Year Published: 2022

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