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Clinical and laboratory characteristics of unintentional carbon monoxide poisoning due to coal stove in children

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Abstract To describe predictors for severe carbon monoxide (CO) poisoning in children due to coal stove. Patients (n = 176) were divided into two groups retrospectively: severe and mild-moderate clinical presentation. Forty-two… Click to show full abstract

Abstract To describe predictors for severe carbon monoxide (CO) poisoning in children due to coal stove. Patients (n = 176) were divided into two groups retrospectively: severe and mild-moderate clinical presentation. Forty-two patients received hyperbaric oxygen (HBO) therapy. No patient died. pH < 7.30 (p = 0.030; OR:1.0211), carboxyhemoglobin (COHb) (p= 0.002; OR:1.0558), and mean platelet volume (MPV) (p = 0.004; OR:1.4695) were significantly different between the groups. COHb > 20%, (AUC: 0.691) was comparable to those for pH (AUC: 0.536) and MPV (AUC: 0.639) (p > 0.05) in ROC analysis. Although COHb, pH and MPV were poor predictors for severe manifestations, performance of MPV was similar to the COHb and pH levels.

Keywords: due coal; coal stove; carbon monoxide; monoxide poisoning

Journal Title: Toxin Reviews
Year Published: 2017

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