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A green and efficient synthesis of 2-thioxoquinazolinone derivatives in water using potassium thiocyanate

ABSTRACT Green chemistry is one of the most important routes for the synthesis of heterocyclic compounds. In this regard, the synthesis of 2-thioxoquinazolinone derivatives was achieved by condensation of versatile… Click to show full abstract

ABSTRACT Green chemistry is one of the most important routes for the synthesis of heterocyclic compounds. In this regard, the synthesis of 2-thioxoquinazolinone derivatives was achieved by condensation of versatile materials including isatoic anhydride, amine and potassium thiocyanate in the green medium of water. This convenient and efficient method affords the desired products with good to excellent yields. GRAPHICAL ABSTRACT

Keywords: thioxoquinazolinone derivatives; chemistry; potassium thiocyanate; synthesis thioxoquinazolinone

Journal Title: Journal of Sulfur Chemistry
Year Published: 2017

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