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ABSTRACT A group of noroxymorphone derivatives were subjected to Gewald reaction conditions to prepare their respective aminothieno products. In refluxing piperidine/ethanol, 1a–g reacted with elemental sulfur and malononitrile to produce… Click to show full abstract
ABSTRACT A group of noroxymorphone derivatives were subjected to Gewald reaction conditions to prepare their respective aminothieno products. In refluxing piperidine/ethanol, 1a–g reacted with elemental sulfur and malononitrile to produce 2a–g in high yields. Reactions took place in one pot and completed within 4–7 h and products precipitated spontaneously in the reaction mixtures. GRAPHICAL ABSTRACT
Keywords:
preparation novel;
gewald reaction;
applying gewald;
reaction preparation;
reaction;
novel aminothieno
Journal Title: Journal of Sulfur Chemistry
Year Published: 2020
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Journal Title: Journal of Sulfur Chemistry
Year Published: 2020
Link to full text (if available)
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recommendations!