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N-Iodosuccinimide mediated intramolecular oxidative C(sp 2)-S bond formation for the synthesis of 2-aminobenzothiazole derivatives

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An extremely efficient synthetic method for the preparation of 2-aminobenzothiazole derivatives starting from arylthioureas by using N-iodosuccinimide has been reported. This protocol features a mild reaction conditions, a short reaction… Click to show full abstract

An extremely efficient synthetic method for the preparation of 2-aminobenzothiazole derivatives starting from arylthioureas by using N-iodosuccinimide has been reported. This protocol features a mild reaction conditions, a short reaction time, and metal-free oxidative conditions for C (sp 2)-S bond construction. GRAPHICAL ABSTRACT

Keywords: intramolecular oxidative; iodosuccinimide mediated; bond; mediated intramolecular; oxidative bond; aminobenzothiazole derivatives

Journal Title: Journal of Sulfur Chemistry
Year Published: 2021

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