LAUSR

ABSTRACT Introduction: Ocular blood flow and haemodynamics are involved in the pathogenesis of several ophthalmic diseases including retinal vascular diseases and glaucoma. Multiple imaging technologies have been developed for measuring and analyzing ocular microcirculation and, among these optical coherence tomography angiography (OCTA) has gained a role in the clinical management of retinal diseases. Areas covered: The aim of this review is to summarize the modalities developed for imaging and measuring ocular blood flow. We conducted a systemic search of NLM Pubmed, Ovid MEDLINE, Ovid Embase and the Cochrane Library. Relevant studies were identified and were used as sources for our study. Expert Commentary: At present there is no gold standard for the measurement of blood flow and mostly qualitative characteristics are used in clinical scenarios. The use of quantitative characteristics is an interesting prospect as these may serve as diagnostic, prognostic or therapeutic biomarkers. The prospect of using OCTA to quantitatively assess ocular blood flow in ophthalmic patients looks promising considering its increasing use in everyday practice and its future potentials.