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A deep dive into future therapies for microcytic anemias and clinical considerations

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ABSTRACT Introduction Microcytic anemias (MA) have frequent or rare etiologies. New discoveries in understanding and treatment of microcytic anemias need to be reviewed. Areas covered Microcytic anemias with a focus… Click to show full abstract

ABSTRACT Introduction Microcytic anemias (MA) have frequent or rare etiologies. New discoveries in understanding and treatment of microcytic anemias need to be reviewed. Areas covered Microcytic anemias with a focus on the most frequent causes and on monogenic diseases that are relevant for understanding biocellular mechanisms of MA. All treatments except gene therapy, with a focus on recent advances. PubMed search with references selected by expert opinion. Expert opinion As the genetic and cellular backgrounds of dyserythropoiesis will continue to be clarified, collaboration with bioengineering of treatments acting specifically at the protein domain level will continue to provide new therapies in hematology as well as oncology and neurology.

Keywords: therapies microcytic; deep dive; microcytic anemias; hematology; dive future; future therapies

Journal Title: Expert Review of Hematology
Year Published: 2023

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