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Global threshold dynamics of an SVIR model with age-dependent infection and relapse

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ABSTRACT A susceptible-vaccinated-infectious-recovered epidemic model with infection age and relapse age has been formulated. We first address the asymptotic smoothness of the solution semiflow, existence of a global attractor, and… Click to show full abstract

ABSTRACT A susceptible-vaccinated-infectious-recovered epidemic model with infection age and relapse age has been formulated. We first address the asymptotic smoothness of the solution semiflow, existence of a global attractor, and uniform persistence of the model. Then by constructing suitable Volterra-type Lyapunov functionals, we establish a global threshold dynamics of the model, which is determined by the basic reproduction number. Biologically, it is confirmed that neglecting the possibility of vaccinees getting infected will over-estimate the effect of vaccination strategies. The obtained results generalize some existing ones.

Keywords: global threshold; age; infection; relapse; model; threshold dynamics

Journal Title: Journal of Biological Dynamics
Year Published: 2017

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