Photo by nci from unsplash
ABSTRACT Oncolytic viruses (OVs) are a novel class of cancer biotherapeutics with the ability to kill cancers and trigger anti-tumor immunity. Using murine models of cancer in pre-clinical proof-of-concept studies,… Click to show full abstract
ABSTRACT Oncolytic viruses (OVs) are a novel class of cancer biotherapeutics with the ability to kill cancers and trigger anti-tumor immunity. Using murine models of cancer in pre-clinical proof-of-concept studies, we found that neoadjuvant OV administration before surgery efficiently prevents relapse, controls metastases and sensitizes tumors to immune checkpoint inhibitors (ICIs).
Keywords:
pre surgical;
surgical oncolytic;
cancer;
improves breast;
oncolytic virotherapy;
virotherapy improves
Journal Title: Oncoimmunology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Oncoimmunology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!