LAUSR

Bimetallic Ag and Cu (1:1 wt %) NPs were synthesized and annealed at various temperatures from 400, 600 and 800 ˚C using chemical reduction techniques. High temperature annealed (800˚C) Ag:Cu sample ratios (5 and 10 wt %) were used as dopant to MoS2. A variety of characterizations were employed to evaluate annealed and doped samples. XRD technique revealed that synthesized samples constitute FCC phase, and a gradual decrease in crystallite size corresponds to improved crystallinity upon heating and doping onto MoS2. FTIR was used for confirmation of functional groups in the products. The particle sizes of heated samples were less than 50 nm and presence of nanosheets in the doped MoS2 were confirmed using FESEM and TEM analysis. An increase in absorption was observed in bimetallic with increasing temperatures while band gap energy decreased. The vibrational property of bimetallic and doped MoS2 atomic layers was studied using Raman. Antimicrobial activity of prepared products was tested on MRSA-superbug with ciprofloxacin antibiotic as reference drug. Furthermore, molecular docking studies employed to unveil the binding interaction pattern of nanoparticle into the active pocket of β-lactamase enzyme suggested it to be a potential inhibitor that can be further evaluated for its enzyme inhibition characteristics.