LAUSR

Objective To determine the prevalence of HIV non-suppression and factors associated with it. Methods Cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV non-suppression, defined as HIV RNA ≥ 200 copies per ml, is documented. The possible association of HIV non-suppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. Results A total of 30,843 adult patients are included; 7,358 of them (23.86 %) have non-suppressed HIV. An association in found between non-suppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, P < 0,001 in all cases. Conclusions HIV non-suppression is still common with the effective antiretroviral treatment nowadays available. HIV non-suppression is associated with HIV risk factor other than sexual, hepatitis C coinfection, and being a smoker, among other factors.