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Optogenetic control of muscles: potential uses and limitations.

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Optogenetics is a technique where a cell is transduced with a light-sensitive ion channel. This technique can be used to control muscle cell contraction in conjunction with commonly used viral… Click to show full abstract

Optogenetics is a technique where a cell is transduced with a light-sensitive ion channel. This technique can be used to control muscle cell contraction in conjunction with commonly used viral vectors. However, this technique has not yet become widely applied. Here, we discuss the mechanisms and techniques involved in opsin transfer to muscle tissue, the clinical applicability of these approaches, and the major limitations facing this technique.

Keywords: muscles potential; control; optogenetic control; potential uses; uses limitations; control muscles

Journal Title: Human gene therapy
Year Published: 2023

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