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High-Definition Transcranial Direct Current Stimulation to Improve of Verbal Retrieval Deficits in Chronic Traumatic Brain Injury.

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Chronic verbal retrieval deficits have been noted in TBI, but no FDA-approved interventions are available. The present study investigated whether 10 sessions of 20 minutes of 1 milliamp anodal HD-tDCS… Click to show full abstract

Chronic verbal retrieval deficits have been noted in TBI, but no FDA-approved interventions are available. The present study investigated whether 10 sessions of 20 minutes of 1 milliamp anodal HD-tDCS targeting preSMA/dACC (compared to sham HD-tDCS) would improve verbal retrieval deficits in TBI patients. Improvements in verbal retrieval processes were observed up to 8 weeks post-treatment. Thus, potential dysfunction to verbal retrieval circuitry in TBI appears amenable to remediation through electromodulation with HD tDCS to the preSMA/dACC. Although further studies clarifying mechanisms by which tDCS brought about these improvements will likely inform refinements in the application of this therapeutic technique, the findings suggest the efficacy of using HD-tDCS to target other systems vulnerable to TBI to improve functioning.

Keywords: high definition; retrieval; retrieval deficits; improve verbal; verbal retrieval; definition transcranial

Journal Title: Journal of neurotrauma
Year Published: 2019

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