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ATP8A2, an ATP-dependent phosphatidylserine flippase, generates and maintains membrane lipid asymmetry and has been linked to severe neurodegenerative disorders. The C-terminus of ATP8A2 promotes proper protein folding and regulates phosphatidylserine… Click to show full abstract
ATP8A2, an ATP-dependent phosphatidylserine flippase, generates and maintains membrane lipid asymmetry and has been linked to severe neurodegenerative disorders. The C-terminus of ATP8A2 promotes proper protein folding and regulates phosphatidylserine flippase activity.
Keywords:
atpase atp8a2;
flippase activity;
terminus atpase;
flippase;
protein folding
Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
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Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
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recommendations!